Histones are the major protein component of Chromatin, they form the nucleosome and are rich in positivley charged amino acids
Latest Histones Publications:
Linker histone subtypes are not generalized gene repressors. Antibodies to the six chicken histone H1 subtypes and the variant histone ... Trollope AF, Sapojnikova N, Thorne AW, Crane-Robinson C, Myers FA,http://dx.doi.org/10.1016/j.bbagrm.2010.08.007 Biochim Biophys Acta. 2010 Aug 25.
Single- pair FRET experiments on nucleosome conformational dynamics. Nucleosomes, the basic units of DNA compaction in eukaryotes, play a ... Buning R, van Noort J,http://dx.doi.org/10.1016/j.biochi.2010.08.010 Biochimie. 2010 Aug 24.
Extracellular DNA traps promote thrombosis. Neutrophil extracellular traps (NETs) are part of the innate immune ... Fuchs TA, Brill A, Duerschmied D, Schatzberg D, Monestier M, Myers DD Jr, Wrobleski SK, Wakefield TW, Hartwig JH, Wagner DD,http://dx.doi.org/10.1073/pnas.1005743107 Proc Natl Acad Sci U S A. 2010 Aug 23.
Nitric Oxide-Mediated Histone Hyperacetylation in Oral Cancer: Target for a Water-Soluble HAT Inhibitor, CTK7A. Altered histone acetylation is associated with several diseases, including ... Arif M, Vedamurthy BM, Choudhari R, Ostwal YB, Mantelingu K, Kodaganur GS, Kundu TK,http://dx.doi.org/10.1016/j.chembiol.2010.06.014 Chem Biol. 2010 Aug 27;17(8):903-913.
Expanding role of the Jumonji C domain as an RNA hydroxylase. JmjC (Jumonji C) domain-containing proteins are known to be an extensive ... Noma A, Ishitani R, Kato M, Nagao A, Nureki O, Suzuki T,http://dx.doi.org/10.1074/jbc.M110.156398 J Biol Chem. 2010 Aug 25.
Decoding the histone H4 lysine 20 methylation mark. The molecular biology of histone H4 lysine 20 (H4K20) methylation, like ... Balakrishnan L, Milavetz B,http://dx.doi.org/10.3109/10409238.2010.504700 Crit Rev Biochem Mol Biol. 2010 Aug 24.
Immunocytological analysis of chromatin in isolated nuclei. All cells in a multicellular organism have the same genetic constitution, ... Pavlova P, Tessadori F, de Jong HJ, Fransz P,http://dx.doi.org/10.1007/978-1-60761-765-5_28 Methods Mol Biol. 2010;655:413-32.
Plant chromatin immunoprecipitation. Development of multicellular organisms is based on specialized gene ... Villar CB, Kohler C,http://dx.doi.org/10.1007/978-1-60761-765-5_27 Methods Mol Biol. 2010;655:401-11.
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. Neutrophils trap and kill bacteria by forming highly decondensed chromatin ... Li P, Li M, Lindberg MR, Kennett MJ, Xiong N, Wang Y,http://dx.doi.org/10.1084/jem.20100239 J Exp Med. 2010 Aug 23.
Mutagenesis of tGCN5 core region reveals two critical surface residues F90 and R140. Tetrahymena General Control Non-Derepressor 5 (tGCN5) is a critical ... Mehta KR, Chan YM, Yang CY, Lee MX, Voloshchuk N, Montclare JK,http://dx.doi.org/10.1016/j.bbrc.2010.08.069 Biochem Biophys Res Commun. 2010 Aug 20.
Histone deacetylase inhibitors: New treatment options for inflammatory joint disease? Histone deacetylase inhibitors (HDIs) are a new class of compounds that ... Toussirot E, Khan KA, Bertolini E, Wendling D, Herbein G,http://dx.doi.org/10.1016/j.jbspin.2010.03.009 Joint Bone Spine. 2010 Aug 20.
In vivo detection of epithelial neoplasia in the stomach using image-guided Raman endoscopy. This study explores the utility of a novel image-guided Raman endoscopy ... Huang Z, Teh SK, Zheng W, Lin K, Ho KY, Teh M, Yeoh KG,http://dx.doi.org/10.1016/j.bios.2010.07.125 Biosens Bioelectron. 2010 Aug 6.
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases. Pioneering work in the 1960s defined prolyl and lysyl hydroxylations as ... Loenarz C, Schofield CJ,http://dx.doi.org/10.1016/j.tibs.2010.07.002 Trends Biochem Sci. 2010 Aug 19.
Replication stress, a source of epigenetic aberrations in cancer? Cancer cells accumulate widespread local and global chromatin changes and ... Jasencakova Z, Groth A,http://dx.doi.org/10.1002/bies.201000055 Bioessays. 2010 Aug 19.
Do different neurons age differently? Direct genome-wide analysis of aging in single identified cholinergic neurons. Aplysia californica is a powerful experimental system to study the entire ... Moroz LL, Kohn AB,http://dx.doi.org/10.3389/neuro.24.006.2010 Front Aging Neurosci. 2010 May 19;2. pii: 6.