Heterochromatin
Latest Heterochromatin Publications:
Histone chaperone asf1 plays an essential role in maintaining genomic stability in fission yeast. The histone H3-H4 chaperone Asf1 is involved in chromatin assembly (or ... Tanae K, Horiuchi T, Matsuo Y, Katayama S, Kawamukai M,http://dx.doi.org/10.1371/journal.pone.0030472 PLoS One. 2012;7(1):e30472. Epub 2012 Jan 26.
Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis. Organismal aging is influenced by a multitude of intrinsic and extrinsic ... Larson K, Yan SJ, Tsurumi A, Liu J, Zhou J, Gaur K, Guo D, Eickbush TH, Li WX,http://dx.doi.org/10.1371/journal.pgen.1002473 PLoS Genet. 2012 Jan;8(1):e1002473. Epub 2012 Jan 26.
Association of the interferon-beta gene with pericentromeric heterochromatin is dynamically regulated during virus infection through a YY1-dependent mechanism. Nuclear architecture as well as gene nuclear positioning can modulate gene ... Josse T, Mokrani-Benhelli H, Benferhat R, Shestakova E, Mansuroglu Z, Kakanakou H, Billecocq A, Bouloy M, Bonnefoy E,http://dx.doi.org/10.1093/nar/gks050 Nucleic Acids Res. 2012 Jan 28.
47,X,idic(Y),inv dup(Y): A Non-Mosaic Case of a Phenotypically Normal Boy with Two Different Y Isochromosomes and Neocentromere Formation. A de novo aberrant karyotype with 47 chromosomes including 2 ... Pasantes JJ, Wimmer R, Knebel S, Munch C, Kelbova C, Junge A, Kieback P, Kupferling P, Schempp W,http://dx.doi.org/10.1159/000335705 Cytogenet Genome Res. 2012 Jan 25.
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and ... Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tonjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, Lindroth A, Jager N, Rausch T, Ryzhova M, Korbel JO, Hielscher T, Hauser P, Garami M, Klekner A, Bognar L, Ebinger M, Schuhmann MU, Scheurlen W, Pekrun A, Fruhwald MC, Roggendorf W, Kramm C, Durken M, Atkinson J, Lepage P, Montpetit A, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel P, Kulozik AE, Zapatka M, Guha A, Malkin D, Felsberg J, Reifenberger G, von Deimling A, Ichimura K, Collins VP, Witt H, Milde T, Witt O, Zhang C, Castelo-Branco P, Lichter P, Faury D, Tabori U, Plass C, Majewski J, Pfister SM, Jabado N,http://dx.doi.org/10.1038/nature10833 Nature. 2012 Jan 29. doi: 10.1038/nature10833.
DNA-RNA hybrid formation mediates RNAi-directed heterochromatin formation. Certain noncoding RNAs (ncRNAs) implicated in the regulation of chromatin ... Nakama M, Kawakami K, Kajitani T, Urano T, Murakami Y,http://dx.doi.org/10.1111/j.1365-2443.2012.01583.x Genes Cells. 2012 Jan 27. doi: 10.1111/j.1365-2443.2012.01583.x.
Polycomb repressive complex 2 targets murine cytomegalovirus chromatin for modification and associates with viral replication centers. Regulation of viral transcription by chromatin structure has emerged as a ... Abraham CG, Kulesza CA,http://dx.doi.org/10.1371/journal.pone.0029410 PLoS One. 2012;7(1):e29410. Epub 2012 Jan 18.
Molecular evolution in non-recombining regions of the Drosophila melanogaster genome. We study the evolutionary effects of reduced recombination on the D. ... Campos JL, Charlesworth B, Haddrill PR,http://dx.doi.org/10.1093/gbe/evs010 Genome Biol Evol. 2012 Jan 23.
Insulators, long-range interactions, and genome function. Insulators are DNA-protein complexes that can mediate interactions in cis ... Yang J, Corces VG,http://dx.doi.org/10.1016/j.gde.2011.12.007 Curr Opin Genet Dev. 2012 Jan 19.
Effects of bisphenol A exposure on the proliferation and senescence of normal human mammary epithelial cells. The carcinogenic activity of bisphenol A (BPA) is responsible for ... Qin XY, Fukuda T, Yang L, Zaha H, Akanuma H, Zeng Q, Yoshinaga J, Sone H, Cancer Biol Ther. 2012 Mar 1;13(5).
The distribution pattern of critically short telomeres in human osteoarthritic knees. ABSTRACT: INTRODUCTION: Telomere shortening is associated with a number ... Harbo M, Bendix L, Bay-Jensen AC, Graakjaer J, Soe K, Andersen TL, Kjaersgaard-Andersen P, Koelvraa S, Delaisse JM,http://dx.doi.org/10.1186/ar3687 Arthritis Res Ther. 2012 Jan 18;14(1):R12.
Late Replication Domains in Polytene and Non-Polytene Cells of Drosophila melanogaster. In D. melanogaster polytene chromosomes, intercalary heterochromatin (IH) ... Belyaeva ES, Goncharov FP, Demakova OV, Kolesnikova TD, Boldyreva LV, Semeshin VF, Zhimulev IF,http://dx.doi.org/10.1371/journal.pone.0030035 PLoS One. 2012;7(1):e30035. Epub 2012 Jan 10.
An Epigenetic Integrator: New Insights into Genome Regulation, Environmental Stress Responses and Developmental Controls by HISTONE DEACETYLASE 6. Histone acetylation ranks with DNA methylation as one of major epigenetic ... Kim JM, Kim To T, Seki M,http://dx.doi.org/10.1093/pcp/pcs004 Plant Cell Physiol. 2012 Jan 17.
Roles of the nuclear lamina in stable nuclear association and assembly of a herpesviral transactivator complex on viral immediate-early genes. ABSTRACT Little is known about the mechanisms of gene targeting within the ... Silva L, Oh HS, Chang L, Yan Z, Triezenberg SJ, Knipe DM,http://dx.doi.org/10.1128/mBio.00300-11 MBio. 2012 Jan 17;3(1). pii: e00300-11. doi: 10.1128/mBio.00300-11. Print
Heterochromatin as an incubator for pathology and treatment non-response: implication for neuropsychiatric illness. Heterochromatin is a higher order assembly that is characterized by a ... Sharma RP, Gavin DP, Chase KA,http://dx.doi.org/10.1038/tpj.2011.64 Pharmacogenomics J. 2012 Jan 17. doi: 10.1038/tpj.2011.64.