The structure of chromatin its self is regulated primarily through acylation and methylation
Latest Chromatin Structure Publications:
Detection and Quantification of DNA Strand Breaks Using the ROPS (Random Oligonucleotide Primed Synthesis) Assay. DNA double strand breaks (DSBs) arise from spontaneous DNA damage due to ... Boyko A, Kovalchuk I,http://dx.doi.org/10.1007/978-1-60761-646-7_17 Methods Mol Biol. 2010;631:237-42.
Detection of changes in global genome methylation using the Cytosine-extension assay. Methylation is a reversible covalent chemical modification of DNA intended ... Boyko A, Kovalchuk I,http://dx.doi.org/10.1007/978-1-60761-646-7_4 Methods Mol Biol. 2010;631:33-9.
Analysis of Locus-Specific Changes in Methylation Patterns Using a COBRA (Combined Bisulfite Restriction Analysis) Assay. DNA methylation is a major mechanism for the reversible control of gene ... Boyko A, Kovalchuk I,http://dx.doi.org/10.1007/978-1-60761-646-7_3 Methods Mol Biol. 2010;631:23-31.
The impact of histone post-translational modifications on developmental gene regulation. Eukaryotic genomic DNA is orderly compacted to fit into the nucleus and to ... Cruickshank MN, Besant P, Ulgiati D,http://dx.doi.org/10.1007/s00726-010-0530-6 Amino Acids. 2010 Mar 5.
Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6. The minichromosome maintenance (Mcm) 2-7 complex is the replicative ... Wei Z, Liu C, Wu X, Xu N, Zhou B, Liang C, Zhu G,http://dx.doi.org/10.1074/jbc.C109.094599 J Biol Chem. 2010 Mar 4.
Symposium 2: Modern approaches to nutritional research challenges Nutritional developmental epigenomics: immediate and long-lasting effects. The phenotype of an individual is the result of complex interactions ... Attig L, Gabory A, Junien C,http://dx.doi.org/10.1017/S002966511000008X Proc Nutr Soc. 2010 Mar 5:1-11.
A plant-specific histone H3 lysine-4 demethylase represses the floral transition in Arabidopsis. Summary Histone demethylation regulates chromatin structure and gene ... Yang W, Jiang D, Jiang J, He Y,http://dx.doi.org/10.1111/j.1365-313X.2010.04182.x Plant J. 2010 Feb 24.
Transcription within Condensed Chromatin: Steric Hindrance Facilitates Elongation. During eukaryotic transcription, RNA-polymerase activity generates ... Becavin C, Barbi M, Victor JM, Lesne A,http://dx.doi.org/10.1016/j.bpj.2009.10.054 Biophys J. 2010 Mar 3;98(5):824-833.
Development and analysis of a germline BAC resource for the sea lamprey, a vertebrate that undergoes substantial chromatin diminution. Over the last several years, the sea lamprey (Petromyzon marinus) has ... Smith JJ, Stuart AB, Sauka-Spengler T, Clifton SW, Amemiya CT,http://dx.doi.org/10.1007/s00412-010-0263-z Chromosoma. 2010 Mar 2.
Birth-and-death long-term evolution promotes histone H2B variant diversification in the male germinal cell line. The rich diversity within each of the five histone families (H1, H2A, H2B, ... Gonzalez-Romero R, Rivera-Casas C, Ausio J, Mendez J, Eirin-Lopez JM,http://dx.doi.org/10.1093/molbev/msq058 Mol Biol Evol. 2010 Mar 1.
Chromatin regulation by RUNX1. The transcription factor RUNX1 is essential for definitive hematopoiesis ... Lichtinger M, Hoogenkamp M, Krysinska H, Ingram R, Bonifer C,http://dx.doi.org/10.1016/j.bcmd.2010.02.009 Blood Cells Mol Dis. 2010 Feb 27.
Effects of heterochromatin in colorectal cancer stem cells on radiosensitivity. Background and Objective: Radiotherapy (RT) is a major non-surgical ... Chen T, Zhang Y, Guo WH, Meng MB, Mo XM, Lu Y, 2010 Mar 5;29(3):270-276.
From Virus Structure to Chromatin: X-ray Diffraction to Three-Dimensional Electron Microscopy. Early influences led me first to medical school with a view to ... Klug A,http://dx.doi.org/10.1146/annurev.biochem.79.091407.093947 Annu Rev Biochem. 2010 Jan 27.
Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State. MeCP2 is a nuclear protein with an affinity for methylated DNA that can ... Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP,http://dx.doi.org/10.1016/j.molcel.2010.01.030 Mol Cell. 2010 Feb 26;37(4):457-468.
A Bird's-Eye View of MeCP2 Binding. In this issue of Molecular Cell, work from Skene, Bird, and colleagues ... Cohen S, Greenberg ME,http://dx.doi.org/10.1016/j.molcel.2010.02.006 Mol Cell. 2010 Feb 26;37(4):451-452.