Chromatin has a major role in gene regulation, the structure of chromatin its self is regulated primarily through acylation and methylation
Latest Chromatin Methylation Publications:
Aberrant Silencing of Cancer Related Genes by CpG Hypermethylation is Independent of their Spatial Organization in the Nucleus. Aberrant promoter DNA-hypermethylation and repressive chromatin ... Easwaran H, Van Neste L, Sen S, Mohammad HP, Pageau Pouliot GJ, Lawrence J, Herman JG, Schuebel KE, Baylin SB,http://dx.doi.org/10.1158/0008-5472.CAN-10-0765 Cancer Res. 2010 Aug 24.
Epigenetics in neurodegeneration: A new layer of complexity. Several diseases are known to have a multifactorial origin, depending not ... Marques SC, Oliveira CR, Pereira CM, Outeiro TF,http://dx.doi.org/10.1016/j.pnpbp.2010.08.008 Prog Neuropsychopharmacol Biol Psychiatry. 2010 Aug 21.
Epigenetic Regulation of Neonatal Cardiomyocytes Differentiation. The relationship between DNA methylation, histone modifications and ... Kou CY, Lau SL, Au KW, Leung PY, Chim SS, Fung KP, Waye MM, Tsui SK,http://dx.doi.org/10.1016/j.bbrc.2010.08.064 Biochem Biophys Res Commun. 2010 Aug 21.
Epigenetic alteration of the NF-kappaB-inducing kinase (NIK) gene is involved in enhanced NIK expression in basal-like breast cancer. Basal-like breast cancers are triple-negative (estrogen receptor negative, ... Yamamoto M, Ito T, Shimizu T, Ishida T, Semba K, Watanabe S, Yamaguchi N, Inoue JI,http://dx.doi.org/10.1111/j.1349-7006.2010.01685.x Cancer Sci. 2010 Aug 24.
CTCF Prevents the Epigenetic Drift of EBV Latency Promoter Qp. The establishment and maintenance of Epstein-Barr Virus (EBV) latent ... Tempera I, Wiedmer A, Dheekollu J, Lieberman PM,http://dx.doi.org/10.1371/journal.ppat.1001048 PLoS Pathog. 2010 Aug 12;6(8). pii: e1001048.
Dicer is associated with ribosomal DNA chromatin in mammalian cells. BACKGROUND: RNA silencing is a common term for pathways utilizing small ... Sinkkonen L, Hugenschmidt T, Filipowicz W, Svoboda P,http://dx.doi.org/10.1371/journal.pone.0012175 PLoS One. 2010 Aug 13;5(8):e12175.
Chromatin Immunoprecipitation (ChIP) to Assay Dynamic Histone Modification in Activated Gene Expression in Human Cells. In response to a variety of extracellular ligands, the STAT (signal ... Buro LJ, Shah S, Henriksen MA,http://dx.doi.org/10.3791/2053 J Vis Exp. 2010 Jul 29;(41). pii: 2053. doi: 10.3791/2053.
Aging changes the chromatin configuration and histone methylation of mouse oocytes at germinal vesicle stage. Aging decreases the fertility of mammalian females. In old oocytes at ... Manosalva I, Gonzalez A,http://dx.doi.org/10.1016/j.theriogenology.2010.06.024 Theriogenology. 2010 Aug 20.
The epigenetic mechanism of mechanically induced osteogenic differentiation. Epigenetic regulation of gene expression occurs due to alterations in ... Arnsdorf EJ, Tummala P, Castillo AB, Zhang F, Jacobs CR,http://dx.doi.org/10.1016/j.jbiomech.2010.07.033 J Biomech. 2010 Aug 20.
Replication stress, a source of epigenetic aberrations in cancer? Cancer cells accumulate widespread local and global chromatin changes and ... Jasencakova Z, Groth A,http://dx.doi.org/10.1002/bies.201000055 Bioessays. 2010 Aug 19.
Do different neurons age differently? Direct genome-wide analysis of aging in single identified cholinergic neurons. Aplysia californica is a powerful experimental system to study the entire ... Moroz LL, Kohn AB,http://dx.doi.org/10.3389/neuro.24.006.2010 Front Aging Neurosci. 2010 May 19;2. pii: 6.
Epigenetic regulation of the endothelial nitric oxide synthase gene in persistent pulmonary hypertension of the newborn rat. OBJECTIVE: Persistent pulmonary hypertension of the newborn (PPHN) is a ... Xu XF, Ma XL, Shen Z, Wu XL, Cheng F, Du LZ,http://dx.doi.org/10.1097/HJH.0b013e32833e08f1 J Hypertens. 2010 Aug 18.
Epigenetic Regulation of Thy-1 by Histone Deacetylase Inhibitor in Rat Lung Fibroblasts. Thy-1 is a cell surface glycoprotein present on normal lung fibroblasts ... Sanders YY, Tollefsbol TO, Varisco BM, Hagood JS,http://dx.doi.org/10.1165/rcmb.2010-0154OC Am J Respir Cell Mol Biol. 2010 Aug 19.
DNA Methylation Regulates Cocaine-Induced Behavioral Sensitization in Mice. The behavioral sensitization produced by repeated cocaine treatment ... Anier K, Malinovskaja K, Aonurm-Helm A, Zharkovsky A, Kalda A,http://dx.doi.org/10.1038/npp.2010.128 Neuropsychopharmacology. 2010 Aug 18.
Trichostatin A and 5-azacytidine both cause an increase in global histone H4 acetylation and a decrease in global DNA and H3K9 methylation during mitosis in maize. ABSTRACT: BACKGROUND: Modifications of DNA and histones in various ... Yang F, Zhang L, Li J, Huang J, Wen R, Ma L, Zhou D, Li L,http://dx.doi.org/10.1186/1471-2229-10-178 BMC Plant Biol. 2010 Aug 18;10(1):178.