Chromatin has various functions including ensuring the stability of DNA, affecting gene expression, and chromosome replication
Latest Chromatin Function Publications:
Elevated expression of MeCP2 in cardiac and skeletal tissues is detrimental for normal development. MeCP2 plays a critical role in interpreting epigenetic signatures that ... Alvarez-Saavedra M, Carrasco L, Sura-Trueba S, Demarchi Aiello V, Walz K, Xavier Neto J, Young JI,http://dx.doi.org/10.1093/hmg/ddq096 Hum Mol Genet. 2010 Mar 4.
Symposium 2: Modern approaches to nutritional research challenges Nutritional developmental epigenomics: immediate and long-lasting effects. The phenotype of an individual is the result of complex interactions ... Attig L, Gabory A, Junien C,http://dx.doi.org/10.1017/S002966511000008X Proc Nutr Soc. 2010 Mar 5:1-11.
A Rat Monoclonal Antibody Against the Chromatin Remodeling Factor CHD5. CHD5 (chromodomain/helicase/DNA-binding protein 5) is a member of the CHD ... Yoshimura S, Yoshimi T, Ohkawa Y, Azuma M, Tachibana T,http://dx.doi.org/10.1089/hyb.2009.0069 Hybridoma (Larchmt). 2010 Feb;29(1):63-6.
RUNX2 Transcription Factor Regulates Gene Expression in Luteinizing Granulosa Cells of Rat Ovaries. The LH surge promotes terminal differentiation of follicular cells to ... Park ES, Lind AK, Dahm-Kahler P, Brannstrom M, Carletti MZ, Christenson LK, Curry TE Jr, Jo M,http://dx.doi.org/10.1210/me.2009-0392 Mol Endocrinol. 2010 Mar 2.
Statistics of protein-DNA binding and the total number of binding sites for a transcription factor in the mammalian genome. BACKGROUND: Transcription factor (TF)-DNA binding loci are explored by ... Kuznetsov VA, Singh O, Jenjaroenpun P,http://dx.doi.org/10.1186/1471-2164-11-S1-S12 BMC Genomics. 2010 Feb 10;11 Suppl 1:S12.
p53 regulates the transcription of its Delta133p53 isoform through specific response elements contained within the TP53 P2 internal promoter. The tumor suppressor p53 protein is activated by genotoxic stress and ... Marcel V, Vijayakumar V, Fernandez-Cuesta L, Hafsi H, Sagne C, Hautefeuille A, Olivier M, Hainaut P,http://dx.doi.org/10.1038/onc.2010.26 Oncogene. 2010 Mar 1.
Regulation of FGF1 gene promoter through transcription factor RFX1. Fibroblast growth factor 1 (FGF1) has been suggested to have an important ... Hsu YC, Liao WC, Kao CY, Chiu IM,http://dx.doi.org/10.1074/jbc.M109.081463 J Biol Chem. 2010 Feb 26.
A Bird's-Eye View of MeCP2 Binding. In this issue of Molecular Cell, work from Skene, Bird, and colleagues ... Cohen S, Greenberg ME,http://dx.doi.org/10.1016/j.molcel.2010.02.006 Mol Cell. 2010 Feb 26;37(4):451-452.
Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis. The rapidly emerging science of epigenetics and epigenomic medicine ... Qureshi IA, Mehler MF,http://dx.doi.org/10.1016/j.nbd.2010.02.005 Neurobiol Dis. 2010 Feb 23.
Neutrophil extracellular traps: how to generate and visualize them. Neutrophil granulocytes are the most abundant group of leukocytes in the ... Brinkmann V, Laube B, Abu Abed U, Goosmann C, Zychlinsky A,http://dx.doi.org/10.3791/1724 J Vis Exp. 2010 Feb 24;(36). pii: 1724. doi: 10.3791/1724.
CDK4, pRB and E2F1: connected to insulin. ABSTRACT: Pancreatic beta-cells are metabolic sensors involved in the ... Fajas L, Blanchet E, Annicotte JS,http://dx.doi.org/10.1186/1747-1028-5-6 Cell Div. 2010 Feb 5;5(1):6.
Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylation. ABSTRACT: BACKGROUND: Studies indicate that the 19S proteasome contributes ... Koues OI, Mehta NT, Truax AD, Dudley RK, Brooks JK, Greer SF,http://dx.doi.org/10.1186/1756-8935-3-5 Epigenetics Chromatin. 2010 Feb 4;3(1):5.
The YEATS domain of Taf14 in Saccharomyces cerevisiae has a negative impact on cell growth. The role of a highly conserved YEATS protein motif is explored in the ... Schulze JM, Kane CM, Ruiz-Manzano A,http://dx.doi.org/10.1007/s00438-010-0523-x Mol Genet Genomics. 2010 Feb 24.
Regulatory T cells: roles of T cell receptor for their development and function. Naturally arising CD4(+)CD25(+) regulatory T cells (Treg cells), which ... Ohkura N, Sakaguchi S,http://dx.doi.org/10.1007/s00281-010-0200-5 Semin Immunopathol. 2010 Feb 24.
Reexpression of hSNF5 in Malignant Rhabdoid Tumor Cell Lines Causes Cell Cycle Arrest through a p21CIP1/WAF1-Dependent Mechanism. Loss of hSNF5 function is usually observed in malignant rhabdoid tumor ... Kuwahara Y, Charboneau A, Knudsen ES, Weissman BE,http://dx.doi.org/10.1158/0008-5472.CAN-09-1922 Cancer Res. 2010 Mar 1;70(5):1854-65. Epub 2010 Feb 23.