Chromatin is the DNA/Protein material which makes up the chromosomes, its modification plays a significant role in the regulation of gene expression.
Latest Chromatin Publications:
PeakSeq enables systematic scoring of ChIP-seq experiments relative to controls. Chromatin immunoprecipitation (ChIP) followed by tag sequencing (ChIP-seq) ... Rozowsky J, Euskirchen G, Auerbach RK, Zhang ZD, Gibson T, Bjornson R, Carriero N, Snyder M, Gerstein MB,http://dx.doi.org/10.1038/nbt.1518 Nat Biotechnol. 2009 Jan 4.
Loss of Class III beta-Tubulin Induced by Histone Deacetylation Is Associated with Chemosensitivity to Paclitaxel in Malignant Melanoma Cells. Overexpression of class III beta-tubulin (TUBB3) is an important mechanism ... Akasaka K, Maesawa C, Shibazaki M, Maeda F, Takahashi K, Akasaka T, Masuda T,http://dx.doi.org/10.1038/jid.2008.406 J Invest Dermatol. 2009 Jan 1.
Ran out of the nucleus for apoptosis. Induction of apoptosis causes active dissipation of the RanGTP gradient ... Wilde A, Zheng Y,http://dx.doi.org/10.1038/ncb0109-11 Nat Cell Biol. 2009 Jan;11(1):11-2.
The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer research. PURPOSE OF REVIEW: The excitement of finding a cancer modulator which is ... Lomberk G, Mathison AJ, Grzenda A, Urrutia R,http://dx.doi.org/10.1097/MOG.0b013e32830b111d Curr Opin Gastroenterol. 2008 Sep;24(5):597-602.
Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1alpha ,25-dihydroxyvitamin D3. The nuclear receptor vitamin D receptor (VDR) is known to associate with ... Saramaki A, Diermeier S, Kellner R, Laitinen H, Vaisanen S, Carlberg C,http://dx.doi.org/10.1074/jbc.M808090200 J Biol Chem. 2009 Jan 3.
Anticancer activity of an essential oil from Cymbopogon flexuosus. The essential oil from a lemon grass variety of Cymbopogon flexuosus was ... Sharma PR, Mondhe DM, Muthiah S, Pal HC, Shahi AK, Saxena AK, Qazi GN,http://dx.doi.org/10.1016/j.cbi.2008.12.004 Chem Biol Interact. 2008 Dec 11.
Resetting and regulation of Flowering Locus C expression during Arabidopsis reproductive development. Summary The epigenetic regulation of the floral repressor FLOWERING LOCUS ... Choi J, Hyun Y, Kang MJ, In Yun H, Yun JY, Lister C, Dean C, Amasino RM, Noh B, Noh YS, Choi Y,http://dx.doi.org/10.1111/j.1365-313X.2008.03776.x Plant J. 2008 Dec 11.
How epigenomics contributes to the understanding of gene regulation in Toxoplasma gondii. How apicomplexan parasites regulate their gene expression is poorly ... Gissot M, Kim K,http://dx.doi.org/10.1111/j.1550-7408.2008.00366.x J Eukaryot Microbiol. 2008 Nov-Dec;55(6):476-80.
Isolation and characterization of DUSP11, a novel p53 target gene. ABSTRACT p53 regulates the expression of genes involved in cell cycle ... Caprara G, Zamponi R, Melixetian M, Helin K,http://dx.doi.org/10.1111/j.1582-4934.2008.00616.x J Cell Mol Med. 2008 Dec 16.
Extracting transcription factor binding sites from unaligned gene sequences with statistical models. BACKGROUND: Transcription factor binding sites (TFBSs) are crucial in the ... Lu CC, Yuan WH, Chen TM,http://dx.doi.org/10.1186/1471-2105-9-S12-S7 BMC Bioinformatics. 2008 Dec 12;9 Suppl 12:S7.
Genome-wide analysis of BP1 transcriptional targets in breast cancer cell line Hs578T. Homeobox genes are known to be critically important in tumor development ... Song Y, Dang C, Fu Y, Lian Y, Hottel J, Li X, McCaffrey T, Fu SW, Int J Biol Sci. 2009;5(1):1-12. Epub 2008 Dec 3.
Transcriptional Regulation of the Human Prostacyclin Receptor Gene Is Dependent on Sp1, PU.1 and Oct-1 in Megakaryocytes and Endothelial Cells. Prostacyclin plays a central role in hemostasis, inflammation and ... Turner EC, Kinsella BT,http://dx.doi.org/10.1016/j.jmb.2008.12.030 J Mol Biol. 2008 Dec 24.
Interaction in vivo between the Two Matrix Attachment Regions Flanking a Single Chromatin Loop. In interphase nuclei as in metaphase chromosomes, the genome is organized ... Eivazova ER, Gavrilov A, Pirozhkova I, Petrov A, Iarovaia OV, Razin SV, Lipinski M, Vassetzky YS,http://dx.doi.org/10.1016/j.jmb.2008.12.022 J Mol Biol. 2008 Dec 14.
Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer. Treatment of advanced prostate cancer with androgen deprivation therapy ... Yang JC, Ok JH, Busby JE, Borowsky AD, Kung HJ, Evans CP,http://dx.doi.org/10.1158/0008-5472.CAN-08-0442 Cancer Res. 2009 Jan 1;69(1):151-60.
Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth. Androgen receptor (AR) is a critical transcription factor that regulates ... Takayama K, Tsutsumi S, Suzuki T, Horie-Inoue K, Ikeda K, Kaneshiro K, Fujimura T, Kumagai J, Urano T, Sakaki Y, Shirahige K, Sasano H, Takahashi S, Kitamura T, Ouchi Y, Aburatani H, Inoue S,http://dx.doi.org/10.1158/0008-5472.CAN-08-3633 Cancer Res. 2009 Jan 1;69(1):137-42.