Chromatin is the DNA/Protein material which makes up the chromosomes, its modification plays a significant role in the regulation of gene expression.
Latest Chromatin Publications:
Atypical neurofibroma and osteosclerotic metastasis. 35-year-old male presented with multiple swellings in left leg, headache, ... Varyani N, Thukral A, Garg S, Gupta KK, Tandon R, Tripathi K,http://dx.doi.org/10.1155/2012/301437 Case Rep Oncol Med. 2012;2012:301437. Epub 2012 Jan 15.
Induction of Cellular Senescence by Doxorubicin Is Associated with Upregulated miR-375 and Induction of Autophagy in K562 Cells. BACKGROUND: Cellular senescence is a specialized form of growth arrest that is ... Yang MY, Lin PM, Liu YC, Hsiao HH, Yang WC, Hsu JF, Hsu CM, Lin SF,http://dx.doi.org/10.1371/journal.pone.0037205 PLoS One. 2012;7(5):e37205. Epub 2012 May 11.
The Kruppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo. The study of chromatin and its regulators is key to understanding and ... Groner AC, Tschopp P, Challet L, Dietrich JE, Verp S, Offner S, Barde I, Rodriguez I, Hiiragi T, Trono D,http://dx.doi.org/10.1074/jbc.M112.350884 J Biol Chem. 2012 May 17.
Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus. Barrett esophagus (BE) is a human metaplastic condition that is the only known ... di Pietro M, Lao-Sirieix P, Boyle S, Cassidy A, Castillo D, Saadi A, Eskeland R, Fitzgerald RC,http://dx.doi.org/10.1073/pnas.1116933109 Proc Natl Acad Sci U S A. 2012 May 17.
Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island. Repression of many tumor suppressor genes in cancer is concurrent with aberrantly ... Zhang Y, Shu J, Si J, Shen L, Estecio MR, Issa JP,http://dx.doi.org/10.1093/nar/gks429 Nucleic Acids Res. 2012 May 17.
Dihydrotestosterone Inhibits Lectin-Like Oxidized-LDL Receptor-1 Expression in Aortic Endothelial Cells via a NF-kappaB/AP-1-Mediated Mechanism. The mechanisms involved in the antiatherosclerotic effects of androgens are ... Qiu Y, Tanaka T, Nawata H, Yanase T,http://dx.doi.org/10.1210/en.2011-1993 Endocrinology. 2012 May 17.
Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice. Transfusion-related acute lung injury (TRALI) is the leading cause of ... Thomas GM, Carbo C, Curtis BR, Martinod K, Mazo IB, Schatzberg D, Cifuni SM, Fuchs TA, von Andrian UH, Hartwig JH, Aster RH, Wagner DD,http://dx.doi.org/10.1182/blood-2012-01-405183 Blood. 2012 May 17.
FOXA1 Is Essential for Aryl Hydrocarbon Receptor-Dependent Regulation of Cyclin G2. The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor ... Ahmed S, Al-Saigh S, Matthews J,http://dx.doi.org/10.1158/1541-7786.MCR-11-0502 Mol Cancer Res. 2012 May;10(5):636-48.
RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation. Evolution of the mammalian sex chromosomes has resulted in a heterologous X and Y ... Gontan C, Achame EM, Demmers J, Barakat TS, Rentmeester E, van Ijcken W, Grootegoed JA, Gribnau J,http://dx.doi.org/10.1038/nature11070 Nature. 2012 Apr 29;485(7398):386-90. doi: 10.1038/nature11070.
VITAMIN D RECEPTOR BINDING, CHROMATIN STATES AND ASSOCIATION WITH MULTIPLE SCLEROSIS. Both genetic and environmental factors contribute to the aetiology of multiple ... Disanto G, Sandve GK, Berlanga-Taylor AJ, Ragnedda G, Morahan JM, Watson CT, Giovannoni G, Ebers GC, Ramagopalan SV,http://dx.doi.org/10.1093/hmg/dds189 Hum Mol Genet. 2012 May 16.
Phf7 controls male sex determination in the Drosophila germline. Establishment of germline sexual identity is critical for production of male and ... Yang SY, Baxter EM, Van Doren M,http://dx.doi.org/10.1016/j.devcel.2012.04.013 Dev Cell. 2012 May 15;22(5):1041-51.
Association of bromodomain BET proteins to the chromatin requires dimerization through the conserved motif B. BET (Bromodomain and Extra Terminal domain) family proteins are unique among ... Garcia-Gutierrez P, Mundi M, Garcia-Dominguez M,http://dx.doi.org/10.1242/jcs.105841 J Cell Sci. 2012 May 17.
Regulation of multiple target genes by miR-1/miR-206 is pivotal for C2C12 myoblast differentiation. microRNAs are short non-coding RNAs involved in post-transcriptional regulation ... Goljanek-Whysall K, Pais H, Rathjen T, Sweetman D, Dalmay T, Munsterberg A,http://dx.doi.org/10.1242/jcs.101758 J Cell Sci. 2012 May 17.
Snail, a transcriptional regulator, represses adiponectin expression by directly binding to an E-box motif in the promoter. OBJECTIVE: Adiponectin is a hormone that modulates many metabolic processes and ... Park YM, Lee YH, Kim SH, Lee EY, Kim KS, Williams DR, Lee HC,http://dx.doi.org/10.1016/j.metabol.2012.04.014 Metabolism. 2012 May 15.
ROS-mediated apoptotic cell death in prostate cancer LNCaP cells induced by biosurfactant stabilized CdS quantum dots. Cadmium sulfide (CdS) quantum dots (QDs) have raised great attention because of ... Singh BR, Singh BN, Khan W, Singh HB, Naqvi AH,http://dx.doi.org/10.1016/j.biomaterials.2012.04.045 Biomaterials. 2012 May 15.