Chromatin is the DNA/Protein material which makes up the chromosomes, its modification plays a significant role in the regulation of gene expression.
Latest Chromatin Publications:
Telomerase modulates Wnt signalling by association with target gene chromatin. Stem cells are controlled, in part, by genetic pathways frequently ... Park JI, Venteicher AS, Hong JY, Choi J, Jun S, Shkreli M, Chang W, Meng Z, Cheung P, Ji H, McLaughlin M, Veenstra TD, Nusse R, McCrea PD, Artandi SE,http://dx.doi.org/10.1038/nature08137 Nature. 2009 Jul 2;460(7251):66-72.
Common variants on chromosome 6p22.1 are associated with schizophrenia. Schizophrenia, a devastating psychiatric disorder, has a prevalence of ... Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I, Dudbridge F, Holmans PA, Whittemore AS, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, Crowe RR, Oksenberg JR, Mirel DB, Kendler KS, Freedman R, Gejman PV,http://dx.doi.org/10.1038/nature08192 Nature. 2009 Jul 1.
Degrees make all the difference: The multifunctionality of histone H4 lysine 20 methylation. Residue and degree-specific methylation of histone lysines along with ... Wang Y, Jia S, Epigenetics. 2009 Jul 5;4(5).
Chking and executing cell division to prevent genomic instability. Eukaryotic cell division is an orderly and timely process involving the ... Peddibhotla S, Rosen JM, Cell Cycle. 2009 Aug 3;8(15).
Induction of Apoptosis by Rhinacanthone Isolated from Rhinacanthus nasutus Roots in Human Cervical Carcinoma Cells. Rhinacanthone, a main bioactive naphthoquinone, isolated from roots of ... Siripong P, Hahnvajanawong C, Yahuafai J, Piyaviriyakul S, Kanokmedhakul K, Kongkathip N, Ruchirawat S, Oku N, Biol Pharm Bull. 2009 Jul;32(7):1251-60.
The physics behind the larger scale organization of DNA in eukaryotes. In this paper, we discuss in detail the organization of chromatin during a ... Emanuel M, Radja NH, Henriksson A, Schiessel H,http://dx.doi.org/10.1088/1478-3975/6/2/025008 Phys Biol. 2009 Jul 1;6(2):25008.
Id1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signalling. The discovery of JAK2V617F as an acquired mutation in the majority of ... Wood AD, Chen E, Donaldson IJ, Hattangadi S, Burke KA, Dawson MA, Miranda-Saavedra D, Lodish HF, Green AR, Gottgens B,http://dx.doi.org/10.1182/blood-2009-02-206573 Blood. 2009 Jul 1.
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. We recently showed that the mammalian genome encodes >1,000 large ... Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, Thomas K, Presser A, Bernstein BE, van Oudenaarden A, Regev A, Lander ES, Rinn JL,http://dx.doi.org/10.1073/pnas.0904715106 Proc Natl Acad Sci U S A. 2009 Jul 1.
C. elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation. Monitoring Editor: William P. Tansey Fos and Jun are components of ... Hiatt SM, Duren HM, Shyu YJ, Ellis RE, Hisamoto N, Matsumoto K, Kariya KI, Kerppola TK, Hu CD,http://dx.doi.org/10.1091/mbc.E08-08-0833 Mol Biol Cell. 2009 Jul 1.
Recruitment of the transcriptional coactivator HCF-1 to viral immediate early promoters during initiation of HSV-1 reactivation from latency. The transcriptional coactivator HCF-1 is critical for expression of ... Whitlow Z, Kristie TM,http://dx.doi.org/10.1128/JVI.01115-09 J Virol. 2009 Jul 1.
Estrogen-induced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells. Kruppel-like factor 5 (KLF5) is implicated in human breast cancer by ... Guo P, Dong XY, Zhao KW, Sun X, Li Q, Dong JT,http://dx.doi.org/10.1002/ijc.24696 Int J Cancer. 2009 Jun 30.
Epigenetic regulation of cytokine gene expression in T lymphocytes. The developmental program of T helper and regulatory T cell lineage ... Lee CG, Sahoo A, Im SH,http://dx.doi.org/10.3349/ymj.2009.50.3.322 Yonsei Med J. 2009 Jun 30;50(3):322-30. Epub 2009 Jun 23.
Targeted deletion of multiple CTCF-binding elements in the human C-MYC gene reveals a requirement for CTCF in C-MYC expression. BACKGROUND: Insulators and domain boundaries both shield genes from ... Gombert WM, Krumm A,http://dx.doi.org/10.1371/journal.pone.0006109 PLoS One. 2009 Jul 1;4(7):e6109.
A Role of CREB in BRCA1 Constitutive Promoter Activity and Aromatase Basal Expression. Aromatase is the rate-limiting enzyme in estrogen biosynthesis and a key ... Ghosh S, Lu Y, Hu Y, Int J Biomed Sci. 2008 Dec 15;4(4):260-265.
A reader for centromeric chromatin. For nucleosome-encoded epigenetic information to be transmitted, an ... Sekulic N, Black BE,http://dx.doi.org/10.1038/ncb0709-793 Nat Cell Biol. 2009 Jul;11(7):793-5.